ABC of Skin Cancer by Sajjad Rajpar, Jerry Marsden

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By Sajjad Rajpar, Jerry Marsden

The ABC of dermis melanoma is designed to spice up GP self assurance within the analysis and referral of pores and skin melanoma, concentrating on differential analysis and customary pitfalls. in response to the most recent great guidance within the united kingdom, this e-book outlines most sensible perform administration in fundamental care, while additionally masking the Australian viewpoint in this melanoma. Chapters on non-surgical therapy and prevention also are integrated.

This new hugely illustrated identify within the profitable ABC sequence presents a concise, authentic and useful review of dermis cancers and pre-cancerous lesions for normal practitioners, junior medical professionals and clinical scholars.

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Tools such as dermatoscopy, which may aid the in vivo diagnosis of melanoma, are increasingly used in clinical practice. OVERVIEW • The commonest locations for melanoma are the legs of women and the trunk of men. • Most melanomas have a history of being new or of having changed in size, shape or colour. • The ABCDE criteria are an easy aide memoir for screening pigmented lesions. They are useful for detecting superficial spreading melanoma, but less useful for nodular melanoma, amelanotic melanoma and early melanoma.

There is a fleshy papillomatous plaque with excessive growth of terminal hair. 1 Clinical characteristics of junctional, compound and intradermal naevi Location of naevus cells History Age of appearance (years) Change in size Examination Type of lesion Size (mm) Colour Border Symmetry Differential diagnosis Junctional naevus Compound naevus Intradermal naevus Dermo-epidermal junction Dermo-epidermal junction and dermis Dermis 5–30 Gradual increase in size as the child grows, and during pregnancy 5–35 Gradual increase in size as the child grows, and during pregnancy ≥ 20 Usually does not change in size Macule 1–5 Light to dark brown – evenly coloured Well demarcated Symmetrical Melanoma, simple lentigo, solar lentigo, freckle Papule with various degrees of elevation 5–10 Light to dark brown – evenly coloured Well demarcated Symmetrical Melanoma, seborrhoeic keratosis, dermatofibroma, haemangioma Papule 2–10 Brown, speckled, pink or skin coloured Well demarcated Symmetrical Skin tag, basal cell carcinoma Fig.

Motley R, Kersey P, Lawrence C. Multiprofessional guidelines for the management of the patient with primary cutaneous squamous cell carcinoma. Br J Dermatol 2002; 146:18–25. National comprehensive cancer network. Clinical practice guidelines in Oncology. 2005. Available at www. pdf Schwartz R. Keratoacanthoma: a clinico-pathologic enigma. Dermatol Surg 2004; 30:326–33. 1 High-risk features in SCC Clinical features Greater than 2 cm in diameter Located on the eyelid, ear, nose, lip, scalp, anogenital Marjolin ulcer Rapid growth Recurrent SCC Histological features Greater than 4 mm deep or Clark level 5 (reaches subcutaneous fat) Poorly differentiated/spindle cell/desmoplastic Perineural invasion Patient features Immunosuppression Chronic lymphocytic leukaemia Relative risk of local recurrence Relative risk of metastasis 2 2–3 – – 3 3 2–3 5 – 4 2 5 2 5 3 5 – – 2 3–4 The presence of these features is associated with an increased risk of local recurrence and metastases.

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