By Russell Schwartz
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Additional resources for Biological Modeling and Simulation - A Survey of Practical Models, Algorithms, and Numerical Methods
Foods obtained from plants and animals contain a variety of compounds containing amines that could be tested for their ability to carry inositol phosphates into cells. 26 B. Q. PHILLIPPY The large number of InsP2, InsP3 and InsP4 isomers identified in animal cells has made quantification of their individual concentrations a tedious prospect. Some effort has been made to determine the amounts of those isomers which are most abundant. 1–2 µM with several-fold increases observed upon stimulation (Shears, 1989).
Copper was the most effective catalyst, and the rate of 6-hydroxydopamine oxidation by copper phytate was increased three-fold in the presence of 100 mM Na2SO4. , 1991; Lee and Hendricks, 1995; 40 B. Q. , 1998; Cornforth, 2002). , 1997). , 1997). Ins(1,2,6)P3, which is the drug α-trinositol and is produced by many plant and microbial phytases, exhibits analgesic and anti-inflammatory properties. , 1998). It might be revealing to investigate the antioxidant and anti-inflammatory potencies of Ins(1,2,3)P3 and Ins(1,2,6)P3 in some model feeding studies.
The metabolic pathways for the synthesis and degradation of InsP6 are multibranched and dependent upon the particular mix of enzymes and substrates present in the same cellular compartment. 2% of the dry weight. InsP6 and InsP5 account for more than 95% of the total inositol phosphates in most raw grains and legumes and predominate in processed foods, which sometimes also contain substantial levels of InsP4 and InsP3. Avocado fruit and some vegetables contain appreciable amounts of InsP6, but very little data is available in this area.