Collected Papers on Wave Mechanics (Second Edition) by Erwin Schrödinger

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By Erwin Schrödinger

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However, it is clear that at the same shear rate, larger cells (corresponding to the S phase of the cell cycle) are intrinsically more viscous (less deformable) than smaller cells (corresponding to the G 1 phase of the cell cycle). Interestingly, even the smallest of the immature cells (GI) were significantly more viscous than their mature counterparts, the neutrophil. Thus, consistent with clinical experience, the presence of immature cells in the circulation is likely to have serious effects on perfusion and oxygen delivery.

Yeung, A Apparent viscosity and cortical tension of blood granulocytes determined by micropipet aspiration. Biophys. 1. 56:151-160; 1989. ; Skalak, T. C. Leukocyte cytoskeletal structure determines capillary plugging and network resistance. Am. J. Physiol. 265:H1670-1678; 1993. Lichtman, M. A. The relationship of excessive white cell accumulation to vascular insufficiency in patients with leukemia. In: H. 1. Meiselman, M. A Lichtman and P. L. LaCelle eds. White Cell Mechanics: Basic Science and Clinical Aspects.

Rp is the pipet radius. Videomicrographs of the time-dependent recovery of a lymphocyte are shown in Figure 5. The relatively large size of the nucleus can be seen. We are presently trying different means to enhance the quality and definition of the videomicrographs. This will allow us to better follow the recovery of the nucleus and to characterize its rheological properties. , 1991 (Figure 6). It is found that one population of the lymphocytes 28 R. Tran-Son-Tay et a1. a Figure 5. Recovery of a Lymphocyte.

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